Fountainbridge | Custom Synthesis

Custom Synthesis

Fountainbridge provides custom synthesis services to customers across the chemical industry, including drug development companies, contract research/manufacturing organisations, catalogue companies, government bodies and academic institutions. We are committed to providing a reliable, fast, cost effective custom synthesis service based on a foundation of technical innovation and clear, open communication

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Fountainbridge specialises in the custom synthesis of organic small molecules including impurities, metabolites, intermediates; and molecules for drug discovery and development. Fountainbridge's chemists have successfully completed hundreds of custom synthesis projects on scales ranging from mg - multi kg.

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Fountainbridge's dedicated team of chemists are based in Shanghai working on projects of scales from mg-multi kg utilising complex chemistry, multi-step synthesis routes and key technologies.

Fountainbridge’s chemists have strengths in the custom synthesis of molecules for drug development, impurity reference standards and metabolites on the mg-100g scale, having successfully completed many challenging synthesis projects for these types of molecules for applications in both pharmaceutical and plant protection

  • Dedicated team of chemists for synthesis and process development
  • Successful track-record in performing challenging, multi-step syntheses
  • Fixed cost synthesis
  • FTE service
  • Small molecule drug development, medicinal chemistry and process development service
  • 32 Fume hoods, 3 kilo labs, one pressure lab
  • Preparative HPLC for separation work

We also have the capabilities and facilities to support process development and scale-up, supporting the manufacture of intermediates and fine chemicals at kg-Mt scale, features include

  • Professional facilities for pilot production
  • 500 litre reactors and 2 x 1000 litres, 2 x 2000L, 2 x 3000L, 2 x 5000L
  • Pressure Lab with 300 L autoclave up to 200 atm
  • Fractional distillation and re-crystallization facilities
  • An experienced team for scale-up
  • Well-equipped with steam, cooling, vacuum systems
  • Waste water treatment and dangerous goods warehouse

Fountainbridge is committed to providing the best possible service to our customers, we provide regular technical updates on the progress of a synthesis project and communicate the challenges, targets and timescales to support our customer's research, planning & development

Fountainbridge utilises a number of analytical techniques in support of our custom synthesis work including 400MHz NMR, HPLC, MS, GC, prep-HPLC, Karl Fischer water content, elemental analysis, optical rotation, particle size analysis and a physical chemical tests; which are all carried out in-house

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